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CRONO S-PID PORTABLE PUMPS
for the treatment of primary immunodeficiencies

The products described in this website are covered by the EU declaration of conformity, so they are intended for the EU market, with the declared intended purpose.
For non-EU markets such as the US, please contact CANÈ S.p.A. to identify the correct product and the corresponding destination of use.

CRONO S-PID serie 4

infusion pumps for the treatment of primary immunodeficiencies. Crono Spid
retro infusion pumps for the treatment of primary immunodeficiencies. Crono Spid

CRONO S-PID 4 20

infusion pumps for the treatment of primary immunodeficiencies. Crono Spid
retro infusion pumps for the treatment of primary immunodeficiencies. Crono Spid

CRONO S-PID 4 50

infusion pumps for the treatment of primary immunodeficiencies. Crono Spid
retro infusion pumps for the treatment of primary immunodeficiencies. Crono Spid

CRONO S-PID 4 100

CRONO S-PID serie 3

CRONO S-PID infusion pumps

Infusion pumps CRONO S-PID are portable syringe pumps intended for subcutaneous administration of immunoglobulins.

The infusion pumps CRONO S-PID PID are a synthesis of high technology and innovative design.
Their small size and light weight make them ideal for use at home, giving the patient the freedom to carry out everyday and leisure activities during the infusion.

The main technical features of the CRONO S-PID pump are:

- The possibility of selecting the programming mode in time or flow:
The feed mechanism, which acts directly on the rubber piston of the reservoir, allows the pump to achieve a high thrust force combined with excellent precision in drug delivery

The CRONO S-PID are equipped with a liquid crystal display that shows information useful to the doctor and patient regarding programming, operation and diagnostics of the pump.

Technical specifications
CRONO S-PID 4 20

Pump dimensions 76 x 49 x 29 mm
Pump weight 115 g, including battery.
Battery Lithium CR 123A 3V (battery life approx. 80 infusions).
Réservoir Dedicated, with 10 and 20 ml capacity and “Luer-Lock” universal safety fitting.
T mode
    Total infusion time programmable from 15 mins to 20 hrs (10 ml syringe) in the following way:
  • from 15 min to 1 h with 5 min increments;
  • from 1 to 20 h with 15 min increments.
    Total infusion time programmable from 30 mins to 20 hrs (20 ml syringe) in the following way:
  • from 30 min to 1 h with 5 min increments;
  • from 1 to 20 h with 15 min increments.
F mode
    Flow rate programmable from 1 ml/h to 40 ml/h in the following way:
  • from 1 to 10 ml/h with 0,1 ml/h increments;
  • from 10 to 40 ml/h with 1 ml/h increments.
Flow rate accuracy +/-2%.
Maximum occlusion pressure 8 bar
Post-occlusion bolus Up to 1,4 ml
Electronic circuit Managed by twin microcontrollers for improved safety
Memory All selected values are automatically stored in a memory which is retained even if the battery is removed from the device.
Display Colour graphical OLED display, 96x64 pixels.
Motor Coreless DC motor. The microcontroller controls the rotation speed using an infrared encoder.
Settings lock Two configurable levels.
Safety circuits They ensure that the device is correctly operational. In case of a fault they generate acoustic signals and messages shown on the display
Ingress protection rating of the pump IP 42
Supplied standard equipment Ambulatory pump with reservoir, infusion pump carry-case, elastic belt, collar strap, fabric case, 2 batteries, battery cover opening tool and user guide.
Guarantee Two years for manufacturing defects.

accessories CRONO S-PID 4 20

Technical specifications
CRONO S-PID 4 50

Pump dimensions 84 x 55 x 42 mm
Pump weight 139 g, including battery.
Battery Lithium CR 123A 3V (battery life approx. 60-80 infusions).
Réservoir Dedicated, with 50 ml capacity and “Luer-Lock” universal safety fitting.
T mode
    Total infusion time programmable from 30 mins to 10 hrs in the following way:
  • from 30 min to 1 h with 5 min increments;
  • from 1 to 10 h with 15 min increments.
F mode
    Flow rate programmable from 5 ml/h to 100 ml/h in the following way:
  • from 5 to 10 ml/h with 0,1 ml/h increments;
  • from 10 to 100 ml/h with 1 ml/h increments.
Flow rate accuracy +/-3%.
Maximum occlusion pressure 4,4 bar
Post-occlusion bolus Up to 1,8 ml
Electronic circuit Managed by twin microcontrollers for improved safety
Memory All selected values are automatically stored in a memory which is retained even if the battery is removed from the device.
Display Colour graphical OLED display, 96x64 pixels.
Motor Coreless DC motor. The microcontroller controls the rotation speed using an infrared encoder.
Settings lock Two configurable levels.
Safety circuits They ensure that the device is correctly operational. In case of a fault they generate acoustic signals and messages shown on the display
Ingress protection rating of the pump IP 42
Supplied standard equipment Ambulatory pump with reservoir, infusion pump carry-case, elastic belt, collar strap, fabric case, 2 batteries, battery cover opening tool and user guide.
Guarantee Two years for manufacturing defects.

accessories CRONO S-PID 4 50

Technical specifications
CRONO S-PID 4 100

Pump dimensions 88 x 59 x 56 mm
Pump weight 140 g, including battery.
Battery Lithium CR 123A 3V (battery life approx. 60-80 infusions).
Réservoir Dedicated, with 100 ml capacity and “Luer-Lock” universal safety fitting.
T mode
    Total infusion time programmable from 20 mins to 20 hrs in the following way:
  • 20 min to 1 h with 5 min increments;
  • 1 to 20 h with 15 min increments.
F mode
    Flow rate programmable from 0,5 ml/h to 300 ml/h in the following way:
  • 5 to 10 ml/h with 0,1 ml/h increments;
  • 10 to 300 ml/h with 1 ml/h increments.
FRC mode
    FRC programmable parameters
  • Number of flows 2 to 5
  • Interval 5 to 20 min with 5 min increments;
  • Flows:
    • 5 ml/h to 10 ml/h with 0,1 ml/h increments;
    • 10 ml/h to 300 ml/h with 1 ml/h increments.
Flow rate accuracy +/-3%.
Maximum occlusion pressure 3,2 bar
Post-occlusion bolus Up to 4 ml
Electronic circuit Managed by twin microcontrollers for improved safety
Memory All selected values are automatically stored in a memory which is retained even if the battery is removed from the device.
Display Colour graphical OLED display, 96x64 pixels.
Motor Coreless DC motor. The microcontroller controls the rotation speed using an infrared encoder.
Settings lock Two configurable levels.
Safety circuits They ensure that the device is correctly operational. In case of a fault they generate acoustic signals and messages shown on the display
Ingress protection rating of the pump IP 42
Supplied standard equipment Ambulatory infusion pump with reservoir, infusion pump carry-case, elastic belt, collar strap, fabric case, 2 batteries, battery cover opening tool and user guide.
Guarantee Two years for manufacturing defects.
pompa infusionale per immunodeficienza primitiva CRONO SPID 4-100
Crono Spid 4 100 con siringa da 100
pompa infusionale per immunodeficienza primitiva CRONO SPID 4-100
Retro Crono Spid 4 100
pompa infusionale per immunodeficienza primitiva CRONO SPID 4-100
Crono Spid 4 100 con siringa da 100

accessories CRONO S-PID 4 100

Technical specifications
CRONO S-PID

REF CRONO S-PID V2
GTIN 08050616613042
Classification Class IIb medical device, according to Rule 11 of Annex IX of the 93/42/EEC European Directive and subsequent changes introduced by the 2007/47/EC European Directive.
Italian Device Repertory Registration 384791/R
Italian Device Classification (CND) Z1204021699
Pump dimensions 3.00 x 1.94 x 1.15 in (76 x 49 x 29 mm)
Pump weight 115 g (4.06 oz.), including battery.
Battery Lithium CR 123A 3V (battery life approx 100 infusions).
Single-use reservoirs Dedicated, with a 10 and 20 ml capacity and a “Luer-Lock” universal safety attachment.
Partial volume Selectable, from 1 to 10 ml in 1 ml increments (10 ml reservoir).
Selectable, from 1 to 20 ml in 1 ml increments (20 ml reservoir).
Flow rate Programmable from: 0.20 ml/h. to 40.00 ml/h.
Available priming volume 1,5 ml.
Flow rate precision +/-2%.
Occlusion pressure 6,0 bar +/-2,0.
Shot volume 22 microlitres (shot: quantity administered for every rotation of the motor).
Post-occlusion bolus Approx 1,2 ml.
Settings memory All settings are automatically stored in a flash memory which is retained even if the device is left without a battery.
Display Liquid crystal display (LCD) (1.1 x 2.8 cm; 0.43 x 1.0 in).
Motor Coreless DC motor, the rotation of which is controlled by an infrared system.
Settings lock Two configurable levels.
Electronic circuit with twin microcontrollers Ensures a more reliable and safer infusion system
Safety circuits These check that the device is functioning correctly, intervening in the event of any anomaly with sounds and messages on the display.
Ingress protection rating IP 42
Equipment supplied Tragbare Pumpe, Tasche für Infusor, Elastikgurt, Stoffbeutel, Umhän geschnur, 2 Batterien (eine bereits in die Pumpe eingesetzt), Hilfsmittel zum Öffnen des Batteriefachs, Benutzerhandbuch.
Guarantee 2 (zwei) Jahre ab Herstellungsdatum.

accessories CRONO S-PID

Technical specifications
CRONO S-PID 30

Pump dimensions 3.14 x 1.85 x 1.18 in (80 x 47 x 30 mm).
Pump weight 125 g, including the battery.
Battery Lithium CR 123A 3V (battery life about 100 infusions).
Dedicated single-use reservoirs With a 30 ml capacity and a "Luer-Lock" universal security attachment.
Quantities that can be administered Selectable, from 1 to 30 ml in 1 ml increments.
Time Mode (delivery time) Selectable, from 25 m. to 300 h.
Flow Rate Mode Selectable, from 0.1 ml/h to 75 ml/h.
Available priming volume 1,5 ml.
Flow rate precision +/-3%.
Occlusion pressure 4,5 bar +/-2.
Single-shot volume 33 microliters (shot: quantity administered for every rotation of the motor).
Post-occlusion bolus About 1,2 ml.
Memory settings All settings are automatically stored in a flash memory which is retained even if the device is left without a battery.
Display Liquid Crystal Display (LCD) (dimensions: 0.43 x 1.0 in; 11 x 28 mm).
Motor Coreless DC motor, the rotation of which is controlled by an infrared system.
Settings lock Two configurable levels.
Electronic circuit with two microcontrollers Ensures a more reliable and safer infusion system.
Safety circuits They check that the device is functioning correctly, intervening in the event of any anomaly with acoustic signals and messages on the display.
Protection rating of the pump IP 42
Equipment supplied Ambulatory infusion pump with a reservoir, infuser carry-case, elastic belt, collar strap, fabric case, two batteries, battery cover opening tool and User Guide.
Guarantee Two years for manufacturing defects.

accessories CRONO S-PID 30

Technical specifications
CRONO S-PID 50

Pump dimensions 3.31 x 2.17 x 1.65 in (84 x 55 x 42 mm).
Pump weight 139 g (4.47 oz.), including battery.
Battery Lithium CR 123A 3V (battery life about 60/80 infusions).
Single-use reservoir With a 50 ml capacity and a “Luer-Lock” universal security attachment
Partial volume Selectable, from 1 to 50 ml in 1 ml increments.
Time Mode (delivery time) Selectable, from 30’ m. to 500 h.
Flow rate Mode Selectable, from 0.1 ml/h to 100 ml/h.
Setting of the number of infusion sites (only in Flow rate Mode) Selectable, from 1 to 5 sites.
Available priming volume 1,5 ml
Flow rate precision +/-3%.
Occlusion pressure 3,0 bar +/-1,5
Shot volume 20 microlitres (shot: quantity administered for every rotation of the motor).
Post-occlusion bolus About 1,8 ml.
Settings memory All settings are automatically entered in a flash memory which is retained even if the device is left without a battery.
Display Liquid Crystal Display (LCD - 0.43 x 1.0 in; 11 x 28 mm).
Motor Coreless DC motor, the rotation of which is controlled by an infrared system.
Settings lock Two configurable levels.
Electronic circuit with twin microcontrollers Ensures a more reliable and safer infusion system.
Safety circuits They check that the device is functioning correctly, intervening in the event of any anomaly with acoustic signals and messages on the display.
Protection rating of the pump IP 42
Supplied standard equipment Ambulatory infusion pump, infuser carry-case, elastic belt, collar strap, fabric case, 2 batteries, battery cover opening tool user guide.
Guarantee Two years for manufacturing defects.

accessories CRONO S-PID 50

Technical specifications
CRONO S-PID 100

Pump dimensions 88 x 59 x 56 mm (3.46 x 2.31 x 2.20 in).
Pump weight 140 g (4.50 oz.), Battery inclusa.
Battery Lithium CR 123A 3V (battery life about 60/80 infusions).
Dedicated single use Reservoir with a 100 ml capacity and a “Luer-Lock” universal security attachment.
Partial volume increments Selectable, from 1 to 100 ml in 1 ml.
Time mode (delivery time) Selectable, from 20’ to 500 h.
Flow rate Mode Programmabile da 0,2 ml/h a 300 ml/h.
Setting of the number of infusion sites (only in Flow rate Mode) Selectable, from 1 to 5 sites.
Available priming volume 3,0 ml.
Flow rate precision +/-3%.
Occlusion pressure 2,2 bar +/-1.
Shot volume 20 microlitres (shot: quantity administered for every rotation of the motor).
Post-occlusion bolus About 4,0 ml.
Settings memory All settings are automatically stored in a flash memory which is retained even if the device is left without a battery. The settings are stored for a period of 10 years, twice the expected life time of the pump.
Display Liquid crystal display (dimensions 11 x 28 mm; 0.43 x 1.0 in).
Motor Coreless DC motor, the rotation of which is controlled by an infrared system.
Settings lock Two configurable levels.
Electronic circuit with twin Microcontrollers Ensures a more reliable and safer infusion system.
Safety circuits These check that the device is functioning correctly, intervening in the event of a any anomaly with sounds and messages on the display.
Ingress protection rating IP 42
Supplied standard equipment Ambulatory pump, carry-case, elastic belt, collar strap, fabric case, 2 batteries (1 of which in the pump), battery-cover opening tool, user guide.
Guarantee Two years for manufacturing defects.

accessories CRONO S-PID 100

Technical specifications
CRONO SUPER PID

Pump dimensions 76 x 49 x 29 mm (3.00 x 1.94 x 1.15 in).
Pump weight 115 g (4.06 oz.), Battery inclusa.
Battery Lithium CR 123A 3V (battery life approx 100 infusions).
Single-use reservoirs Dedicated, with a 10 and 20 ml capacity and a “Luer-Lock” universal safety attachment.
Quantities that can be administered Selectable, from 1 to 10 ml in 1 ml increments (10 ml reservoir).
Selectable, from 1 to 20 ml in 1 ml increments (20 ml reservoir).
Duration of infusion
    Programmable from:
  • 15 min to 99 h (10 ml reservoir)
  • 30 min to 99 h (20 ml reservoir)
Available priming volume 1,5 ml.
Flow rate precision +/-2%.
Occlusion pressure 6,0 bar +/-2,0.
Shot volume 22 microlitres (shot: quantity administered for every rotation of the motor).
Post-occlusion bolus Approx 1,2 ml.
Settings memory All selected settings values are automatically saved in memory and are retained even when there are no batteries in the device
Display Liquid Crystal Display (LCD - 1.1 x 2.8 cm; 0.43 x 1.0 in).
Motor Coreless DC motor, the rotation of which is controlled by an infrared system.
Settings lock Two configurable levels.
Electronic circuit with twin microcontrollers Ensures a more reliable and safer infusion system.
Safety circuits Verify the correct operation of the device, intervening in the event of any anomaly with acoustic signals and messages on the display.
Protection rating of the pump IP 42
Supplied equipment Ambulatory pump, infuser carry-case, elastic belt, supporting cord, fabric pouch, 2 batteries, battery cover opening tool and user manual.
Guarantee Two years for manufacturing defects.

accessories CRONO SUPER PID